About

The MODEL-AD consortium comprises two research centers with complementary approaches to generating new mouse models that more faithfully recapitulate features of Alzheimer's disease in humans. Mouse models are phenotyped using standardized neuropathology, 'omics, and behavioral measures. The Model AD Explorer shares summaries of phenotypic data for available mouse models. Visit Model Overview to see the models and results that are currently available. New models and data will be incorporated as available, and additional data can be accessed through the AD Knowledge Portal. Additional information is available in the Model AD Explorer Resources documentation. We encourage you to use the data and insights presented in the Model AD Explorer to help you select the appropriate mouse model for your research along with the following acknowledgement statement(s):   For data and models generated by the UCI MODEL-AD Center:
The results published here are in whole or in part based on data obtained from the AD Knowledge Portal ( https://adknowledgeportal.synapse.org/ ). The UCI MODEL-AD Center was established with funding from The National Institute on Aging (U54 AG054345-01 and AG054349). Aging studies are also supported by the Nathan Shock Center of Excellence in the Basic Biology of Aging (NIH P30 AG0380770).
  For data and models generated by the IU/Jax/Pitt MODEL-AD Center:
The results published here are in whole or in part based on data obtained from the AD Knowledge Portal ( https://adknowledgeportal.synapse.org/ ).The IU/JAX/PITT MODEL-AD Center was established with funding from The National Institute on Aging (U54 AG054345). Contact us:
  The Model AD Explorer is funded by the National Institute on Aging. It is developed and maintained by Sage Bionetworks. If you have questions, suggestions, or feedback about the Model AD Explorer, please contact us at: .