Model AD Explorer — Next-generation models of Alzheimer's Disease
The Model AD Explorer is a publicly accessible scentific application
developed and maintained by Sage Bionetworks, a 501(c)(3) nonprofit
biomedical research organization, with funding from the National Institute on Aging (NIA).
The Model AD Explorer is part of the broader
AD Knowledge Portal ecosystem at
adknowledgeportal.org.
About the Model AD Explorer
The Model AD Explorer hosts summaries of phenotypic data for in vivo models of Alzheimer's
Disease (AD) to enable researchers to select the most appropriate model to use for their
research. The Model AD Explorer was initially developed with support of the NIA's Model
Organism Development and Evaluation for Late-onset Alzheimer’s Disease (MODEL-AD)
Consortium.
About the AD Knowledge Portal
The AD Knowledge Portal (adknowledgeportal.org) is an open-access database developed by
Sage Bionetworks that disseminates data, tools, and analytical results generated by
multiple National Institute on Aging-funded programs focused on aging, dementia, and
Alzheimer's disease. The portal hosts data and resources generated across 100+ grant
projects in 10+ NIA-supported programs and centers, including multi-omic data from human
samples and experimental model systems.
The portal was developed as part of the Accelerating Medicines Partnership in Alzheimer's
Disease (AMP-AD) program between the NIH and several nonprofit organizations and
pharmaceutical companies, and has since expanded to include data from additional
NIA-funded consortia.
What You Can Do on the Model AD Explorer
- Explore detailed phenotypic characterization results for 15+ AD mouse models.
-
Compare genome-wide differential RNA expression results for the available mouse models.
-
See how changes in mouse model gene expression correlate with changes in gene expression
in human AD patients.
- View pathology and biomarker evidence for the available mouse models.
- Search for mouse models by name, JAX ID, RRID, or by modified gene.
- Find results for additional mouse models as they become available.
-
See results for other AD model organisms developed by the NIA-funded Marmo-AD and MPS-AD
consortia as they become available.
Nonprofit Identity
Sage Bionetworks
A 501(c)(3) nonprofit research organization
EIN: 26-4489946
Seattle, Washington, USA
sagebionetworks.org
Trust Center — Terms of Service, Privacy Policy, financial statements, and governance
documents
Learn More
This static content is provided for search engines and users with JavaScript disabled. For
the full Model AD Explorer experience, please enable JavaScript in your browser.
